STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bma-ula-1NEDD8-activating enzyme E1 regulatory subunit. (538 aa)    
Predicted Functional Partners:
Bma-rfl-1
BMA-RFL-1, isoform b.
   
0.999
bma-ned-8
BMA-NED-8.
   
 0.994
bma-ubc-12
BMA-UBC-12; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.982
bma-jhdm-1
BMA-JHDM-1.
    
 0.932
bma-dcn-1
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
   
 0.811
bma-atg-3
Autophagy-related protein 3.
   
 0.809
bma-smo-1
Small ubiquitin-related modifier.
   
 0.798
bma-rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.780
Bma-ddb-1
BMA-DDB-1, isoform e; BMA-DDB-1, isoform h.
   
 
 0.779
bma-rbx-1
BMA-RBX-1.
   
 
 0.777
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.