STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bm5082Bm5082, isoform a. (937 aa)    
Predicted Functional Partners:
Bm1_49360
Bm16946.
   
 
 0.655
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
    
 
 0.628
Bm1_11930
Uncharacterized protein.
    
 
 0.611
A0A5S6PCI2
Uncharacterized protein.
   
 
 0.567
A0A5S6PEI4
Bm5498.
   
 
 0.567
Bma-mus-101
BMA-MUS-101, isoform c.
   
 
 0.529
Bma-hsr-9
BMA-HSR-9, isoform c.
   
 
 0.504
bma-hmg-20
BMA-HMG-20, isoform a.
   
  
 0.502
Bma-smk-1
BMA-SMK-1, isoform d.
   
 
 0.479
A0A5S6PCF6
Uncharacterized protein.
   
 
 0.473
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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