STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hspBMA-HSP-17; Small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (152 aa)    
Predicted Functional Partners:
HSP70
Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.
   
 0.702
Bm1_40970
Bm16888; Belongs to the small heat shock protein (HSP20) family.
  
 0.600
A0A5S6PAI1
Thioredoxin peroxidase 1.
   
  
 0.516
TSA1
Peroxiredoxin 1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
  
 0.516
Bma-deb-1
BMA-DEB-1; Vinculin.
   
 
 0.514
VINC_BRUMA
Vinculin; Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane.
   
 
 0.514
A0A5S6PRR6
Uncharacterized protein.
   
 
 0.501
bma-hsp-90
BMA-DAF-21.
   
 0.497
Bm1_20215
Bm5434.
   
 0.497
bma-hsp-1
BMA-HSP-1; Belongs to the heat shock protein 70 family.
   
 0.473
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.