STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bm1_16975BMA-SIR-2.4. (246 aa)    
Predicted Functional Partners:
bma-com-1
BMA-COM-1.
    
 0.713
bma-pcyt-2.1
Bm13987.
 
    
 0.648
Bm1_38355
NAD-dependent deacetylase SIRT1, putative.
  
 
0.619
Bma-acs-19
Acetyl-coenzyme A synthetase.
    
 0.590
bma-hda-11
BMA-HDAC-11.
    
 
 0.569
Bma-his-56
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.555
Bm4113
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.555
bma-his-71.2
Histone H3; Belongs to the histone H3 family.
    
 0.549
bma-fkh-2
BMA-FKH-2, isoform b; BMA-FKH-2, isoform c.
    
 0.506
Bm1_49360
Bm16946.
  
 
 0.499
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.