STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5S6PNY5Spectrin beta chain. (2357 aa)    
Predicted Functional Partners:
bma-spc-1
BMA-SPC-1.
   
0.991
A0A5S6PFL3
Uncharacterized protein.
   
 0.978
Bma-trpa-1
Poly [ADP-ribose] polymerase.
   
 0.902
Bma-copb-1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.711
bma-sel-9
BMA-SEL-9.
     
 0.681
Bm1_52975
ER lumen protein-retaining receptor.
     
 0.668
bma-let-60
BMA-LET-60.
   
  0.611
A0A5S6PE19
Uncharacterized protein.
    
 0.603
bma-chc-1
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 
 0.599
Bm1_31335
Non-specific serine/threonine protein kinase.
    
  0.591
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.