STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5S6PY80BMA-CKU-70, isoform d. (617 aa)    
Predicted Functional Partners:
A0A5S6PGB9
BMA-LIG-4, isoform b.
   
 0.959
Bma-cku-80
BMA-CKU-80.
   
 0.951
Bm1_54420
BMA-CKU-80.
   
 0.951
bma-mre-11
BMA-MRE-11; Belongs to the MRE11/RAD32 family.
   
 0.934
Bm1_49360
Bm16946.
   
 
 0.887
Bm10789
Bm10789, isoform g.
   
 0.850
Bma-hsr-9
BMA-HSR-9, isoform c.
    
 0.849
Bm1_40385
Bm4003.
    
 0.825
Bm1_26765
DNA ligase.
   
 0.776
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 
 0.724
Your Current Organism:
Brugia malayi
NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis
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