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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QJS9Uncharacterized protein. (1646 aa)    
Predicted Functional Partners:
A0A044TQE0
Uncharacterized protein.
    
 0.920
A0A044RDE8
Uncharacterized protein.
   
 0.860
A0A044S7Z1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.839
A0A2K6VKU0
PID domain-containing protein.
   
 0.834
A0A044TY20
Ncstrn_small domain-containing protein.
    
 0.820
A0A044UGX7
Uncharacterized protein.
    
 0.820
A0A044R0N6
Uncharacterized protein.
    
 0.810
A0A044RI49
Uncharacterized protein.
    
 0.808
A0A044V9P0
Uncharacterized protein.
    
 0.783
A0A044R8E7
Uncharacterized protein.
   
 0.752
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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