Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QJS9Uncharacterized protein. (1646 aa)    
Predicted Functional Partners:
A0A044TQE0
Uncharacterized protein.
    
 0.961
A0A044S7Z1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.896
A0A044UGX7
Uncharacterized protein.
    
 0.895
A0A2K6VKU0
PID domain-containing protein.
   
 0.895
A0A044TY20
Ncstrn_small domain-containing protein.
    
 0.873
A0A044R0N6
Uncharacterized protein.
    
 0.848
A0A044RI49
Uncharacterized protein.
    
 0.839
A0A044V9P0
Uncharacterized protein.
    
 0.824
A0A044T6Q4
Uncharacterized protein.
    
 0.742
A0A044THD7
Uncharacterized protein.
    
 0.708
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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