Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QL51PRELI/MSF1 domain-containing protein. (200 aa)    
Predicted Functional Partners:
A0A044QP41
Uncharacterized protein.
    
 0.995
A0A044TMG9
PRELI/MSF1 domain-containing protein.
    
 0.971
A0A044UF56
Uncharacterized protein.
   
 
 0.810
A0A044S0D1
Prohibitin.
   
 
 0.750
A0A044RJG2
ABC1 domain-containing protein.
    
 
 0.746
A0A044U5S0
Uncharacterized protein.
    
 
 0.746
A0A044QQK3
START domain-containing protein.
   
 0.721
A0A044U730
ANK_REP_REGION domain-containing protein.
      
 0.697
A0A044V4I7
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
    
 
 0.693
A0A044TYR4
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
    
 
 0.629
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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