Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QL72Chloride channel protein. (840 aa)    
Predicted Functional Partners:
A0A044RAV7
Uncharacterized protein.
   
 0.668
A0A044U8D0
AA_TRNA_LIGASE_II domain-containing protein.
     
 0.569
A0A044R6G1
UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
    
  0.554
A0A044RLJ3
Uncharacterized protein; Belongs to the adenylate kinase family.
    
  0.554
A0A044S7A0
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
    
  0.554
A0A044SR00
Uncharacterized protein.
    
  0.554
A0A044RCQ1
Uncharacterized protein.
    
 0.529
A0A044UF17
Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family.
      
 0.522
A0A044SZS0
Uncharacterized protein.
      
 0.509
A0A044RZ36
CULT domain-containing protein.
    
 
 0.476
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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