Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QLR2CRIM domain-containing protein. (641 aa)    
Predicted Functional Partners:
A0A044QZA3
RICTOR_N domain-containing protein.
   
 0.998
A0A044QZA9
RICTOR_V domain-containing protein.
   
 0.998
A0A044R465
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.998
A0A044UWU6
WD_REPEATS_REGION domain-containing protein.
    
 0.998
A0A044V0L6
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    
 0.984
A0A158N8L2
Non-specific serine/threonine protein kinase.
    
 0.975
A0A044R3W2
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.971
A0A044V4B7
Protein kinase domain-containing protein.
    
 0.963
A0A044TCZ0
Uncharacterized protein.
    
 
 0.918
A0A044SVP4
Raptor_N domain-containing protein.
   
 0.900
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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