Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044QSW4Carboxypeptidase; Belongs to the peptidase S10 family. (473 aa)    
Predicted Functional Partners:
A0A044RC12
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.952
A0A158N8B3
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.952
A0A044U3H2
Beta-galactosidase.
   
 0.926
cpz
Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed (Probable). Required for the degradation and shedding of the old cuticle (Probable) ; Belongs to the peptidase C1 family.
   
 0.921
A0A044T246
Angiotensin-converting enzyme.
     
 0.915
A0A044QVP1
Uncharacterized protein.
    
 0.910
A0A2K6VT82
Uncharacterized protein; Belongs to the heat shock protein 70 family.
    
 
 0.892
A0A044T4Y2
Uncharacterized protein.
    
 
 0.867
A0A044UMJ9
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.867
A0A2K6VSD8
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.867
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
Server load: low (22%) [HD]