A0A044RAG2 protein (Onchocerca volvulus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

A0A044RAG2

Uncharacterized protein. (561 aa)

Predicted Functional Partners:

A0A044V487

0.977

A0A044U0Y3

0.965

A0A158N8Q0

0.957

ran-1

0.957

A0A2K6VDW5

0.937

A0A044RL70

0.936

A0A044TPF9

0.919

A0A2K6VYV5

0.919

A0A044R7P9

0.836

A0A2K6VI00

0.831

Your Current Organism:

Onchocerca volvulus

NCBI taxonomy Id: 6282
Other names: O. volvulus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A044R7P9	A0A044RAG2	A0A044R7P9	A0A044RAG2	C2-C2_1 domain-containing protein.	Uncharacterized protein.	0.836
A0A044R7P9	A0A2K6VI00	A0A044R7P9	A0A2K6VI00	C2-C2_1 domain-containing protein.	Phosphodiesterase delta-like protein; Belongs to the PDE6D/unc-119 family.	0.714
A0A044RAG2	A0A044R7P9	A0A044RAG2	A0A044R7P9	Uncharacterized protein.	C2-C2_1 domain-containing protein.	0.836
A0A044RAG2	A0A044RL70	A0A044RAG2	A0A044RL70	Uncharacterized protein.	Importin N-terminal domain-containing protein.	0.936
A0A044RAG2	A0A044TPF9	A0A044RAG2	A0A044TPF9	Uncharacterized protein.	SUMO-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.919
A0A044RAG2	A0A044U0Y3	A0A044RAG2	A0A044U0Y3	Uncharacterized protein.	Uncharacterized protein.	0.965
A0A044RAG2	A0A044V487	A0A044RAG2	A0A044V487	Uncharacterized protein.	Uncharacterized protein.	0.977
A0A044RAG2	A0A158N8Q0	A0A044RAG2	A0A158N8Q0	Uncharacterized protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.957
A0A044RAG2	A0A2K6VDW5	A0A044RAG2	A0A2K6VDW5	Uncharacterized protein.	RanBD1 domain-containing protein.	0.937
A0A044RAG2	A0A2K6VI00	A0A044RAG2	A0A2K6VI00	Uncharacterized protein.	Phosphodiesterase delta-like protein; Belongs to the PDE6D/unc-119 family.	0.831
A0A044RAG2	A0A2K6VYV5	A0A044RAG2	A0A2K6VYV5	Uncharacterized protein.	Importin N-terminal domain-containing protein.	0.919
A0A044RAG2	ran-1	A0A044RAG2	P38544	Uncharacterized protein.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.957
A0A044RL70	A0A044RAG2	A0A044RL70	A0A044RAG2	Importin N-terminal domain-containing protein.	Uncharacterized protein.	0.936
A0A044RL70	A0A044TPF9	A0A044RL70	A0A044TPF9	Importin N-terminal domain-containing protein.	SUMO-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.734
A0A044RL70	A0A044U0Y3	A0A044RL70	A0A044U0Y3	Importin N-terminal domain-containing protein.	Uncharacterized protein.	0.985
A0A044RL70	A0A044V487	A0A044RL70	A0A044V487	Importin N-terminal domain-containing protein.	Uncharacterized protein.	0.991
A0A044RL70	A0A158N8Q0	A0A044RL70	A0A158N8Q0	Importin N-terminal domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.990
A0A044RL70	A0A2K6VDW5	A0A044RL70	A0A2K6VDW5	Importin N-terminal domain-containing protein.	RanBD1 domain-containing protein.	0.971
A0A044RL70	A0A2K6VYV5	A0A044RL70	A0A2K6VYV5	Importin N-terminal domain-containing protein.	Importin N-terminal domain-containing protein.	0.917
A0A044RL70	ran-1	A0A044RL70	P38544	Importin N-terminal domain-containing protein.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.990