A0A044RF99 protein (Onchocerca volvulus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

A0A044RF99

Uncharacterized protein. (152 aa)

Predicted Functional Partners:

A0A044RDE8

0.772

A0A044T2W7

0.683

A0A044S6L7

0.670

A0A044S6M0

0.670

A0A044UZJ1

0.556

A0A044SRA0

0.548

A0A044UPK6

0.546

A0A044SFF3

0.528

A0A2K6WFI3

0.528

A0A044RMV8

0.524

Your Current Organism:

Onchocerca volvulus

NCBI taxonomy Id: 6282
Other names: O. volvulus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A044RDE8	A0A044RF99	Uncharacterized protein.	Uncharacterized protein.	0.772
A0A044RDE8	A0A044SFF3	Uncharacterized protein.	INB domain-containing protein.	0.773
A0A044RDE8	A0A044SRA0	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.795
A0A044RDE8	A0A044UPK6	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.732
A0A044RDE8	A0A2K6WFI3	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.773
A0A044RF99	A0A044RDE8	Uncharacterized protein.	Uncharacterized protein.	0.772
A0A044RF99	A0A044RMV8	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.524
A0A044RF99	A0A044S6L7	Uncharacterized protein.	Uncharacterized protein.	0.670
A0A044RF99	A0A044S6M0	Uncharacterized protein.	Uncharacterized protein.	0.670
A0A044RF99	A0A044SFF3	Uncharacterized protein.	INB domain-containing protein.	0.528
A0A044RF99	A0A044SRA0	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.548
A0A044RF99	A0A044T2W7	Uncharacterized protein.	Uncharacterized protein.	0.683
A0A044RF99	A0A044UPK6	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.546
A0A044RF99	A0A044UZJ1	Uncharacterized protein.	Uncharacterized protein.	0.556
A0A044RF99	A0A2K6WFI3	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.528
A0A044RMV8	A0A044RF99	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.524
A0A044RMV8	A0A044SRA0	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.568
A0A044RMV8	A0A044UZJ1	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.747
A0A044S6L7	A0A044RF99	Uncharacterized protein.	Uncharacterized protein.	0.670
A0A044S6L7	A0A044S6M0	Uncharacterized protein.	Uncharacterized protein.	0.997