Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044RGB2DUF1981 domain-containing protein. (1778 aa)    
Predicted Functional Partners:
A0A044R1G8
PHB domain-containing protein.
    
 
 0.974
A0A2K6VW44
Uncharacterized protein.
      
 0.723
A0A044S0D1
Prohibitin.
    
 
 0.694
A0A044UZ53
Cyclic nucleotide-binding domain-containing protein.
   
  
 0.692
A0A044QKN8
Uncharacterized protein.
      
 0.690
A0A044V9X6
OBG-type G domain-containing protein.
      
 0.660
A0A044RQ65
Uncharacterized protein.
      
 0.659
A0A044U4H9
SLC12 domain-containing protein.
      
 0.546
A0A044U4I5
Uncharacterized protein.
      
 0.546
A0A044TR31
SOCS box domain-containing protein.
      
 0.479
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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