Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A044S005Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (499 aa)    
Predicted Functional Partners:
A0A044UL77
Homeobox domain-containing protein.
   
 0.992
A0A044VDH8
Ski_Sno domain-containing protein.
    
 
 0.985
A0A044RK73
Homeobox domain-containing protein.
   
 0.976
A0A044TYQ1
Homeobox domain-containing protein.
   
 0.931
A0A044RG61
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.839
A0A044QST1
Paired domain-containing protein.
    
 0.817
A0A044THY8
Paired domain-containing protein.
    
 0.817
A0A044RZL4
ENTH domain-containing protein.
    
   0.807
A0A158N890
HMG box domain-containing protein.
    
 
 0.801
A0A044T9Y9
Uncharacterized protein.
    
 
 0.800
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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