Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A044SC46SF4 helicase domain-containing protein. (785 aa)    
Predicted Functional Partners:
A0A044VG49
SURP motif domain-containing protein.
   
 
 0.948
A0A044VE71
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
 
 0.946
A0A044SCA6
Uncharacterized protein.
    
   0.880
A0A044S9V2
Endonuclease.
    
 
 0.841
A0A044V7D6
Uncharacterized protein.
     
 0.832
A0A044RB82
Uncharacterized protein.
    
  0.817
A0A044RHG5
RING-type domain-containing protein.
    
 
 0.812
A0A158N7W9
Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
    
 
 0.794
A0A044VBL5
DUF155 domain-containing protein.
      
 0.783
A0A2K6W2R5
HMG box domain-containing protein.
     
 0.762
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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