Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044SC47tRNA_int_endo domain-containing protein. (332 aa)    
Predicted Functional Partners:
A0A044SD73
Uncharacterized protein.
   
 0.987
A0A044UGW7
Uncharacterized protein.
    
 0.983
A0A2K6WFY3
Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.
    
 0.950
A0A044V090
RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.
    
 0.776
A0A2K6WJR2
Uncharacterized protein.
   
    0.765
A0A044QYN8
DALR_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.733
A0A044QUB6
Uncharacterized protein.
  
  
 0.698
A0A044SVS8
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
      
 0.661
A0A044S2Q6
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
  
  
 0.613
A0A158N8Q3
Homeobox domain-containing protein.
    
   0.599
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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