Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A044SC81Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa)    
Predicted Functional Partners:
A0A044U172
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
    
 
 0.930
A0A044V0K9
SMAP domain-containing protein.
    
   0.886
A0A044SPV0
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
    
   0.869
A0A044RAM8
MoCF_biosynth domain-containing protein.
    
 
 0.844
A0A044SCB0
PUM-HD domain-containing protein.
    
   0.812
A0A044SCB7
Uncharacterized protein.
    
   0.812
A0A044S1K4
Uncharacterized protein.
      
 0.733
A0A2K6VZT4
Flavokinase domain-containing protein.
      
 0.707
A0A044S6L7
Uncharacterized protein.
      
 0.703
A0A044S6M0
Uncharacterized protein.
      
 0.703
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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