Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044SCB0PUM-HD domain-containing protein. (599 aa)    
Predicted Functional Partners:
A0A044UYU7
Uncharacterized protein.
    
 
 0.926
A0A044UUU1
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
    
 
 0.881
A0A044QPV6
Nanos-type domain-containing protein; Belongs to the nanos family.
   
 
 0.867
A0A044TJ90
Nanos-type domain-containing protein; Belongs to the nanos family.
   
 
 0.867
A0A044V4G0
Uncharacterized protein.
   
 
 0.858
A0A044U172
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
    
 
 0.849
A0A044TAZ4
Endo/exonuclease/phosphatase domain-containing protein.
   
 
 0.848
A0A044UWZ1
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner.
    
 
 0.842
A0A044V454
Endo/exonuclease/phosphatase domain-containing protein.
   
 
 0.842
A0A044RKF2
Uncharacterized protein.
    
 
 0.840
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.