Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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A0A044SCU5Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (99 aa)    
Predicted Functional Partners:
A0A044RLR6
SAGA-associated factor 11; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
    
 0.977
A0A044RAK7
Ubiquitin carboxyl-terminal hydrolase.
    
 0.968
A0A2K6W2U4
Uncharacterized protein.
    
 0.964
A0A044QW54
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.961
A0A044TVM4
TFIID_20kDa domain-containing protein.
   
 0.960
A0A044UH42
Uncharacterized protein.
   
 0.960
A0A044UQS9
Uncharacterized protein.
   
 0.959
A0A044S0R9
SANT domain-containing protein.
    
 0.954
A0A044SW90
Uncharacterized protein.
    
 0.954
A0A044QRH1
Uncharacterized protein.
    
 0.953
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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