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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A044STR4Uncharacterized protein. (71 aa)    
Predicted Functional Partners:
A0A044TPF9
SUMO-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.828
A0A044TXN9
Uncharacterized protein.
    
  0.683
A0A044RLW3
ThiF domain-containing protein.
    
 0.627
A0A044SHS3
Uncharacterized protein.
    
  0.611
A0A044U470
SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.
    
 0.576
A0A044V2H1
Ubiquitin-like domain-containing protein.
   
  0.575
A0A044RJV8
Uncharacterized protein.
    
  0.560
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
    
  0.454
A0A044TLE7
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.401
A0A044VI60
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.401
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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