Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
Score
A0A044SWK1Elongation of very long chain fatty acids protein. (284 aa)    
Predicted Functional Partners:
A0A044SQX3
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
    
 0.754
A0A044QPX0
Uncharacterized protein.
    
 0.743
A0A044SZ86
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
    
 0.700
A0A044V479
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.681
A0A044TXS3
Carrier domain-containing protein.
   
 
 0.678
A0A044T6S7
Uncharacterized protein.
   
 0.642
A0A2K6WCG8
Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.
   
 0.642
A0A2K6WDQ3
Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.
   
 0.642
A0A044QVQ6
Uncharacterized protein.
     
 0.617
A0A044UT56
AMP-binding domain-containing protein.
   
 
 0.576
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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