Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044SWX6SURF6 domain-containing protein. (613 aa)    
Predicted Functional Partners:
A0A044QUI8
Uncharacterized protein.
   
 
 0.996
A0A044V2L4
RRM domain-containing protein.
   
 
 0.994
A0A044SW74
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
   
 
 0.992
A0A044V6Y7
Protein MAK16 homolog; Belongs to the MAK16 family.
   
 
 0.991
A0A044TIM1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.990
A0A044U2N3
Uncharacterized protein.
   
 
 0.990
A0A044US13
Brix domain-containing protein.
   
 
 0.990
A0A044R0E4
Brix domain-containing protein.
   
 
 0.989
A0A044UG04
Uncharacterized protein.
   
 
 0.989
A0A2K6WLZ6
Brix domain-containing protein.
   
 
 0.989
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
Server load: low (12%) [HD]