A0A044TP91 protein (Onchocerca volvulus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

A0A044TP91

Uncharacterized protein. (410 aa)

Predicted Functional Partners:

A0A044V334

0.982

A0A044V741

0.963

A0A044UKV4

0.959

A0A044UXG5

0.955

A0A2K6VRR4

0.935

A0A044UKV1

0.930

A0A044TFU1

0.929

A0A044RDM1

0.912

A0A044SQ82

0.908

A0A044V309

0.907

Your Current Organism:

Onchocerca volvulus

NCBI taxonomy Id: 6282
Other names: O. volvulus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A044RDM1	A0A044TP91	Uncharacterized protein.	Uncharacterized protein.	0.912
A0A044RDM1	A0A044V309	Uncharacterized protein.	Uncharacterized protein.	0.898
A0A044RDM1	A0A2K6VRR4	Uncharacterized protein.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.804
A0A044SQ82	A0A044TP91	Uncharacterized protein.	Uncharacterized protein.	0.908
A0A044TFU1	A0A044TP91	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.929
A0A044TFU1	A0A2K6VRR4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.505
A0A044TP91	A0A044RDM1	Uncharacterized protein.	Uncharacterized protein.	0.912
A0A044TP91	A0A044SQ82	Uncharacterized protein.	Uncharacterized protein.	0.908
A0A044TP91	A0A044TFU1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.929
A0A044TP91	A0A044UKV1	Uncharacterized protein.	Uncharacterized protein.	0.930
A0A044TP91	A0A044UKV4	Uncharacterized protein.	Flavoprotein domain-containing protein.	0.959
A0A044TP91	A0A044UXG5	Uncharacterized protein.	Uncharacterized protein.	0.955
A0A044TP91	A0A044V309	Uncharacterized protein.	Uncharacterized protein.	0.907
A0A044TP91	A0A044V334	Uncharacterized protein.	Uncharacterized protein.	0.982
A0A044TP91	A0A044V741	Uncharacterized protein.	BHLH domain-containing protein.	0.963
A0A044TP91	A0A2K6VRR4	Uncharacterized protein.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.935
A0A044UKV1	A0A044TP91	Uncharacterized protein.	Uncharacterized protein.	0.930
A0A044UKV1	A0A044UXG5	Uncharacterized protein.	Uncharacterized protein.	0.897
A0A044UKV1	A0A044V334	Uncharacterized protein.	Uncharacterized protein.	0.935
A0A044UKV1	A0A044V741	Uncharacterized protein.	BHLH domain-containing protein.	0.821