Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044TY20Ncstrn_small domain-containing protein. (720 aa)    
Predicted Functional Partners:
A0A044V9P0
Uncharacterized protein.
    
 0.999
A0A044S7Z1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.998
A0A044T6Q4
Uncharacterized protein.
   
 0.998
A0A044RI49
Uncharacterized protein.
   
 0.996
A0A044R8E7
Uncharacterized protein.
    
 0.970
A0A044SV50
Uncharacterized protein.
    
 0.940
A0A044TIP2
A4_EXTRA domain-containing protein.
    
 0.936
A0A044QJS1
Uncharacterized protein.
    
 0.925
A0A044QJS9
Uncharacterized protein.
    
 0.873
A0A044UGX7
Uncharacterized protein.
    
 
 0.856
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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