Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044TY45DUF2012 domain-containing protein. (230 aa)    
Predicted Functional Partners:
A0A044SQT1
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 
 0.991
A0A044SAR4
ER membrane protein complex subunit 3.
   
 
 0.990
A0A044SG87
Uncharacterized protein.
   
 
 0.988
A0A044SJM6
Uncharacterized protein.
    
 
 0.987
A0A044VI14
EMC1_C domain-containing protein.
    
 
 0.987
A0A044R6E0
TPR_REGION domain-containing protein.
   
 
 0.984
A0A2K6W3U5
MPN domain-containing protein.
   
 
 0.981
A0A044UVW4
Uncharacterized protein.
      
 0.826
A0A158N7R5
Uncharacterized protein.
    
 
 0.753
A0A044T7P5
Uncharacterized protein.
   
   0.752
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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