Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A044U032Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (487 aa)    
Predicted Functional Partners:
A0A2K6VJ94
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.994
A0A044V9X1
Uncharacterized protein.
  
 0.989
A0A044UTH7
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.987
A0A044UEP7
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.966
A0A044R2Y2
Uncharacterized protein.
    
 0.951
A0A044USL6
Acetyl-coenzyme A synthetase.
  
 
 0.943
A0A044QWC9
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.936
A0A044SYT5
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.931
A0A044R6E3
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.927
A0A044S6I2
Uncharacterized protein.
  
 
 0.923
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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