Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A044UB02Uncharacterized protein. (2714 aa)    
Predicted Functional Partners:
A0A044T677
Uncharacterized protein.
    
 0.629
A0A044UZ80
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
    
 0.606
A0A044V9A7
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
    
 0.606
A0A044R7E2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
     
  0.553
A0A044UU49
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
     
  0.553
A0A044QMG4
C-type lectin domain-containing protein.
    
  0.529
A0A044R7V8
Uncharacterized protein.
    
  0.529
A0A044RJC4
Uncharacterized protein.
    
  0.529
A0A044RS96
DUF1768 domain-containing protein.
    
  0.529
A0A044S074
C-type lectin domain-containing protein.
    
  0.529
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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