STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A044VFH0MIF4G domain-containing protein. (1123 aa)    
Predicted Functional Partners:
A0A044S759
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.978
A0A044SKP8
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.969
A0A044SEL9
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.925
A0A044UWX6
RRM domain-containing protein.
   
 0.903
A0A044UFE4
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.900
A0A2K6VP08
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
   
 0.900
A0A2K6VXL2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.
    
 0.888
A0A044S0C4
S1 motif domain-containing protein.
   
 0.884
A0A2K6VDN4
Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.
   
 0.878
A0A044S5Q5
Uncharacterized protein.
   
 0.870
Your Current Organism:
Onchocerca volvulus
NCBI taxonomy Id: 6282
Other names: O. volvulus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.