STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mloBPutative restriction modification gene,; Function unclear. (485 aa)    
Predicted Functional Partners:
hsdM
Site-specific DNA-methyltransferase (adenine-specific); METHYLATION OF SPECIFIC ADENINE RESIDUES; REQUIRED FOR BOTH RESTRICTION AND MODIFICATION ACTIVITIES (BY SIMILARITY), TREMBL:Q7VCN2 (55% identity). InterPro (IPR002296): N6 adenine-specific DNA methyltransferase,N12 class. InterPro (IPR003356): N-6 DNA methylase. InterPro (IPR003665): Type I restriction-modification system M subunit. Pfam (PF02384): N-6 DNA Methylase. Pfam (PF02506): Type I restriction modification system, M protein; High confidence in function and specificity.
 
    0.909
hsdS
Type I site-specific deoxyribonuclease; S subunit, DNA SPECIFICITY SUBUNIT REQUIRED FOR RESTRICTION AND MODIFICATION, TREMBL:Q9AAH7 (31% identity); TREMBL:Q8PIJ8 (28% identity). Pfam (PF01420): Type I restriction modification DNA specificity domain. InterPro (IPR000055): Restriction modification system DNA specificity domain; High confidence in function and specificity.
  
    0.893
hsdR
Type I site-specific deoxyribonuclease; SUBUNIT R IS REQUIRED FOR BOTH NUCLEASE AND ATPASE ACTIVITIES BUT NOT FOR MODIFICATION (BY SIMILARITY),TREMBL:Q9AAH5 (64% identity); TREMBL:Q8FUH0 (40% identity). InterPro (IPR001410): DEAD/DEAH box helicase TIGRFAM (TIGR00348): Type I site-specific deoxyribonuclease, HsdR family; High confidence in function and specificity.
  
    0.839
azo1728
Conserved hypothetical secreted protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.
   
    0.658
ycjD
Hypothetical protein ycjD,50% identity(65% similarity) to SwissProt;P45736. Has PF04480, Protein of unknown function (DUF559);IPR007569; No SIgnal Peptide or TMH present. vsr: DNA mismatch endonuclease (vsr).
 
  
  0.574
azo0009
Transcriptional regulatory protein, 35% identity to TrEMBL;Q89JK0. Has Prosite, PS01117; HTH_MARR_1 domain; The marR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH)domain of about 135 amino acids present in transcription regulators of the marR/slyA family,involved in the development of antibiotic resistance; Function unclear.
 
  
  0.559
azo0008
Conserved hypothetical protein. Homology to RB11641 of R.baltica of 42% (tremble:Q7TTG8). No domains predicted. No TMHs. No signal peptide.
       0.502
azo0839
SWI/SNF family helicase Pfam: Helicase conserved C-terminal domain; Specificity unclear.
 
     0.431
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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