STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0020Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.745
gltR
Probable transcriptional regulator, LysR family; HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.704
azo1835
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.680
azo1543
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.671
azo3003
Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership.
  
     0.662
rbcR
Trans-acting transcriptional regulator of RuBisCO genes expression Putative HTH-type transcriptional regulator Contains 1 HTH lysR-type DNA-binding domain,belonds to the LysR family InterPro: Bacterial regulatory protein LysR family ModE_repress: ModE molybdate transport 32% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1; High confidence in function and specificity.
  
     0.574
iorA
Probable isoquinoline 1-oxidoreductase, alpha subunit Homology to iroA of B. diminuta of 58% (sprot|IORA_BREDI). InterPro: [2Fe-2S] binding domain (IPR002888); Ferredoxin (IPR001041) Pfam: 2FE-2S iron-sulfur cluster binding domein, [2Fe-2S] binding domain no signal peptide no TMHs; Specificity unclear.
       0.518
iorB
Putative isoquinoline 1-oxidoreductase, beta subunit Homology to iorB of B. diminuta of 34% (sprot|IORB_BREDI). InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus (IPR000674) Pfam: Aldehyde oxidase and xanthine dehydrogenase signal peptide no TMHs; Family membership.
       0.508
azo1281
Probable transcriptional regulator, LysR family proteins.57% Identity to TrEMBL;Q9HYK6, Q87XZ5, Q88MD6. Has PF03466, LysR substrate binding domain;IPR005119,LysR_subst; The structure of this domain is known and is IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family,groups together a range of proteins, including ampR, catM,catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR [...]
  
     0.493
azo2360
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.484
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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