STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iorAProbable isoquinoline 1-oxidoreductase, alpha subunit Homology to iroA of B. diminuta of 58% (sprot|IORA_BREDI). InterPro: [2Fe-2S] binding domain (IPR002888); Ferredoxin (IPR001041) Pfam: 2FE-2S iron-sulfur cluster binding domein, [2Fe-2S] binding domain no signal peptide no TMHs; Specificity unclear. (152 aa)    
Predicted Functional Partners:
iorB
Putative isoquinoline 1-oxidoreductase, beta subunit Homology to iorB of B. diminuta of 34% (sprot|IORB_BREDI). InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus (IPR000674) Pfam: Aldehyde oxidase and xanthine dehydrogenase signal peptide no TMHs; Family membership.
 0.999
xdhB
Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity.
 
  
  0.982
azo0023
Conserved hypothetical protein (Xanthine like-dehydrogenase accessory factor). Homology to Rsc1464 (hyp. protein) of R. solanacearum of 66% (CAD15165). InterPro: DUF182 Pfam: uncharacterized BCR, COG1975 no signal peptide no TMHs.
 
 
 0.966
azo0024
Conserved hypothetical protein; Purine catabolism protein pucB. TREMBL:Q8XZ0: 40% identity, 47% similarity Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase. FUNCTION: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) (By similarity). PATHWAY: Molybdenum cofactor biosynthesis. SUBCELLULAR LOCATION: Cytoplasmic (By similarity). SIMILARITY: Belongs to the mobA family. Pfam:UPF0007:Uncharacterized protein family UPF000 ispD: 4-diphosphocytidyl-2C-met [...]
 
 
 0.964
nahG
Salicylate hydroxylase (EC 1.14.13.1) (Salicylate 1-monooxygenase). Similar to TREMBL:Q8Z5B1 (62% identity); TREMBL:Q8X657 (62% identity); TREMBL:Q8ZNM3 (62% identity). Pfam (PF01360): Monooxygenase. TMHMM reporting one transmembrane helix; High confidence in function and specificity.
  
 
 0.923
xdhC
Xanthine dehydrogenase protein, probable (chaperone); High confidence in function and specificity.
 
 
 0.871
azo0325
Putative flavocytochrome protein. 48% FAD_binding_6.IPR001433; Oxred_FAD/NAD(P). Pfam:PF00970; FAD_binding_6; 1.PF00175; NAD_binding_1; 1. TMhelix: 6. Siganl peptide: present; Function unclear.
   
    0.833
napG
Probable ferredoxin-type protein napG. Homology to napG of E. coli of 57% (sprot|NAPG_ECOLI). Involved in electron transfer in a wide variety of metabolic reactions. InterPro: MauM/NapG family ferredoxin-type protein (IPR004494); 7 Fe ferredoxin (IPR000813); 4Fe-4S ferredoxin; iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain Tigrfam: mauM_napG: MauM/NapG family ferredoxin-type protein no signal peptide no TMHs; High confidence in function and specificity.
    
 0.669
amiC1
Aliphatic amidase expression-regulating protein,AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to sprot|AMIC_PSEAE (31%) and to trembl|P74390 (50%).Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
   
    0.663
amiC2
Putative aliphatic amidase expression-regulating protein; AmiC regulates the expression of the inducible aliphatic amidase activity in Pseudomonas aeruginosa. Similar to trembl|Q87VQ0 (80%) and to sprot|AMIC_PSEAE (27%). Pfam (PF01094): Receptor family ligand binding region SignalP reporting Signal peptide; Specificity unclear.
   
    0.663
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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