STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltRProbable transcriptional regulator, LysR family; HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity. (296 aa)    
Predicted Functional Partners:
ampR
Probable transcriptional regulator, LysR family; Probable HTH-type transcriptional activator ampR. Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (ampC) in the presence of beta-lactams and induces it in the absence of them. Similar to SWISSPROT: sprot|AMPR_PSEAE (34% Pseudomonas aeruginosa,HTH-type transcriptional activator AmpR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.747
azo1636
HTH-type transcriptional regulator,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.724
yeaT
Putative transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.707
azo0020
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.704
blaA
Probable transcriptional regulator, LysR family; HTH-type transcriptional regulator blaA (Beta-lactamase regulatory protein blaA). Positive regulator of the expression of the gene (blab) for beta-lactamase. Similar to SWISSPROT: sprot|BLAA_PROVU (32% Proteus vulgaris, HTH-type transcriptional regulator BlaA) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.701
azo0132
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.696
azo2867
Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 44% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear.
  
     0.695
bdhR
Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.694
azo2567
Putative LysR-family transcriptional regulator protein.62% identity to TrEMBL;Q63NK9,Q8XQV8,Q62B59,Q8VL17. PF00126, Bacterial regulatory helix-turn-helix protein, lysR family;IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse,but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB,lysR, metR, mkaC, mleR, nahR, nhaR, nodD, n [...]
  
     0.658
gstR1
Putative transcriptional regulator. Homology to gstR of R. leguminosarum of 37% (tremble:Q52827). Has PF00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family.IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC,iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR,nodD, [...]
  
     0.640
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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