STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0033Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 42% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide. (162 aa)    
Predicted Functional Partners:
azo0034
Conserved hypothetical secreted protein. Homology to PP2042 of P. putida of 34% (TrEMBL;Q88L93) Has PF06980:(IPR010727)Protein of unknown function (DUF1302);This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. No TMHs signal peptide present; Conserved hypothetical protein.
       0.645
azo0035
Conserved hypothetical secreted protein. Homology to PA3421 of P. aeruginosa of 50% (TrEMBL;Q9HYI4) Has (IPR010752)PF07044:Protein of unknown function (DUF1329);This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs signal peptide present; Conserved hypothetical protein.
       0.628
frlR
Putative GntR-family transcriptional regulator,; Family membership.
  
  
 0.590
azo0032
Conserved hypothetical protein. Homology to nfa21510 of Nocardia farcinica of 31% (trembl:Q5YXU4). No domains predicted. No TMHs. No signal peptide.
 
 
 
0.578
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
  
 
 0.547
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.543
azo0038
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. EntA,a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase enzyme,is involved in the third stage of enterobactin biosynthesis and converts isochorismate to 2,3-dihydroxybenzoic acid (DHBA), SWISSPROT:Q10855 (37% identity); TREMBL:Q89M15 (36% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. InterPro (IPR003560): 2,3-dihydro-2,3-dihydroxybenzoate dehydroge [...]
    
 0.480
csdB
Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear.
  
  
  0.471
azo0036
Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 40% (trembl|Q88I01). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide no TMHs; Function unclear.
       0.464
azo0037
Probable exporter of RND superfamily; Putative membrane protein MJ1562. TREMBL:Q88LB6: 47% identity, 63% similarity InterPro:IPR000731; SSD_5TM InterPro: HMGCR/Patched 5TM box Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide absent. Presence of 12 transmembrane helices; Family membership.
       0.464
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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