STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0057Conserved hypothetical secreted protein. Homology to BPSS2323 of Burkholderia pseudomallei of 45% (trembl:Q63HU7). no domains predicted. singal peptide. no TMHs; Conserved hypothetical protein. (269 aa)    
Predicted Functional Partners:
azo0056
Conserved hypothetical membrane protein. Homology to cv3942 of C. violaceum of 30% (trembl|Q7NR42) InterPro: DUF214 (IPR003838) Pfam: Predicted permease This is a family of predicted permeases and hypothetical transmembrane proteins. One member has been shown to transport lipids targeted to the outer membrane across the inner membrane, a step which requires ATP. Signal peptide 3 TMHs; Conserved hypothetical protein.
 
 
 
 0.972
azo0055
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:O54136 (41% identity); TREMBL:Q8RCZ7 (40% identity). Pfam (PF00005): ABC transporter. TC (3.A.1): The ATP-binding Cassette (ABC) Superfamily; Family membership.
 
 
 
 0.903
azo0058
Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide TMHs inside of the signal peptide.
       0.788
azo3176
Permease component of an ABC-transporter system; Region start changed from 3485680 to 3485581 (99 bases).
 
 
 
 0.759
lolE3
Permease component of an ABC transporter system; Part of a lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope); Specificity unclear.
 
 
 
 0.742
azo1243
Conserved hypothetical N-acetylmuramoyl-L-alanine amidase. Homology to amiC of R. solanaceraum of 50% (trembl|Q8XWD5) CELL-WALL HYDROLASE PROBABLY INVOLVED IN CELL-WALL HYDROLYSIS SEPTATION OR RECYCLING (BY SIMILARITY). Pfam: N-acetylmuramoyl-L-alanine amidase no signal peptide no TMHs; Family membership.
  
 
   0.609
azo2226
Probable N-acetylmuramoyl-L-alanine amidase amiA precursor, 28% identity to TrEMBL;Q823N1. 26% identity to SwissProt;P36548 Has SMART;SM00646, Ami_3. Signal Peptide present. Has PF01520; N-acetylmuramoyl-L-alanine amidase; IPR002508 Amidase_3_hydro; This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls.
  
 
   0.599
azo3286
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q82SR3 (67% identity); TREMBL:Q92NU9 (48% identity); SWISSPROT:Q58206 (45% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR00359 [...]
 
 
 
 0.590
macB
ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.586
azo1256
Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases); Family membership.
  
     0.539
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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