STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0065Conserved hypothetical protein; 64% similarity with ABC-type multidrug transport system, ATPase and permease components [Dechloromonas aromatica RCB]. and. (178 aa)    
Predicted Functional Partners:
azo0066
Probable enoyl-CoA hydratase/isomerase; Enoyl-CoA hydratase and 3-2trans-enoyl-CoA isomerase are two enzymes involved in fatty acid metabolism. ECH catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA and ECI shifts the 3- double bond of the intermediates of unsaturated fatty acid oxidation to the 2-trans position.In Escherichia coli (gene fadB) and Pseudomonas fragi (gene faoA), ECH and ECI are also part of a multifunctional enzyme which contains both a HCDH and a 3-hydroxybutyryl-CoA epimerase domain. InterPro: Enoyl-CoA hydratase/isomerase Entry name TREMBL:Q8PMW0 P [...]
       0.773
azo2116
Probable Serine hydrolase-like protein (EC 3.1.-.-). TREMBL:Q8Y0A9: 49% identity, 63% similarity. Pfam: abhydrolase; thioesterase TIGRFAM: murB: UDP-N-acetylenolpyruvoylglucosamine No transmembrane helix (predicted by TMHMM); Function unclear.
  
     0.630
polC
DNA polymerase III polC-type (EC 2.7.7.7) (PolIII). Required for replicative DNA synthesis. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). InterPro: Exonuclease dnaq: DNA polymerase III epsilon subun; High confidence in function and specificity.
       0.558
azo0064
Probable permease; Hypothetical protein ydiK.Integral membrane protein (potential). similarity:belongs to the upf0118 (perm) family TREMBL:Q7WQ94: 68% identity; 81% similarity. PIR:AD2790; AD2790.C97569; C97569. InterPro:IPR000585; Hemopexin. IPR002549; UPF0118. Pfam: PF01594; UPF0118; 2A0604s01: protein-export membrane pro Pfam: presence of DUF20 domain and branched chain amino acid transport. TIGRFAM: general nitrate transport. Signal P predicted signal peptide and TMHMM predicted transmembrane helices; Function unclear.
       0.526
azo3230
Probable Hypothetical protein Ta0487. trembl:Q7W4W1:50% identity, 62% similarity InterPro:IPR001453; MoCF_biosynth. Pfam: PF00994; MoCF_biosynth; 1. Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon molyb_syn: molybdenum cofactor synthe No signal peptide. No transmembrane helices; Function unclear.
  
     0.497
nagH
Putative ring hydroxylating beta subunit; NagH: probable salicylate-5-hydroxylase small oxygenase component oxidoreductase protein. Involved in conversion of Naphthalene to gentisate. Aromatic compounds degradation; Family membership.
  
     0.432
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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