STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0073Putative MFS permease; Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Probable sugar-proton symporter transmembrane protein ProP proline/betaine transporter. Low homology to the hypothetical protein ycxA (ORF5)involved in the biosynthesis of the pepitde antibiotic Bacitracin in B. subtilis. Signal peptide; Specificity unclear. (403 aa)    
Predicted Functional Partners:
azo0072
Putative two component sensor histidine kinase,; Specificity unclear.
 
     0.723
azo0071
Sigma-54 dependent response regulator,; Specificity unclear.
       0.635
azo0074
Hypothetical protein yfbK. The von Willebrand factor is a large multimeric glycoprotein found in blood plasma. Mutant forms are involved in the aetiology of bleeding disorders [1]. In von Willebrand factor, the type A domain (vWF) is the prototype for a protein superfamily. trembl:Q8P6Q2: 55% identity; 66% similarity InterPro:IPR002016; Peroxidase. IPR002035; VWF_A. Pfam: PF00092; VWA; 1. SMART: SM00327; VWA; 1. cdhD: CO dehydrogenase/acetyl-CoA syn Signal peptide present (0.927 probability); SignalP predicted. No transmembrane helices (TMHMM predicted); Function unclear.
       0.516
rpoE
Probable RNA polymerase sigma-E factor (sigma-24),; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
       0.516
azo0076
Conserved hypothetical membrane protein. Homology to BB3269 of Bordetella bronchiseptica of 31% (trembl|Q7WHD9(SRS)). No domains predicted. no signal peptide 1 TMH; Conserved hypothetical protein.
       0.516
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
     
 0.482
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
   
 
 0.453
azo0070
Hypothetical membrane protein. no homology to the data bank. no domains predicted.signal peptide. 1 TMHs.
       0.443
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
    
 0.428
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.