STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBrtcB protein, 57% identical(70% similairty) to TrEMBL;Q7NZ85 TrEMBL;Q8FCS7(56% identity). Has IPR001233;UPF0027(PF01139, Uncharacterized protein family):A number of uncharacterized proteins including Escherichia coli rtcB, Mycobacterium tuberculosis MtCY441.01., Caenorhabditis elegans F16A11.2 and Methanococcus jannaschii MJ0682 belong to this family. Has no Signal peptide or TMH present; High confidence in function and specificity. (402 aa)    
Predicted Functional Partners:
cca1
tRNA-nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
  
 0.935
azo0078
Hypothetical protein. Weak homology with hits over entire length. PS50821; PAZ domain present(Prosite).
       0.507
azo0077
Hypothetical protein. No Good homologs. No Domains/Features/Motifs reported present.
       0.455
creD
Inner membrane protein CreD; CreD confers tolerance to colicin E2. Similar to SWISSPROT:P08369 (35% identity). TMHMM reporting six transmembrane helices; High confidence in function and specificity.
  
     0.428
prfB
Peptide chain release factor; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
  
  
 0.414
rhlE1
ATP-dependent RNA helicase; Family membership; Belongs to the DEAD box helicase family.
   
 0.403
rhlE2
Putative ATP-dependent RNA helicase rhlE; Family membership; Belongs to the DEAD box helicase family.
   
 0.403
deaD
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
 0.403
rhlE3
Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
   
 0.403
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.