STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo0081Conserved hypothetical membrane protein. Homology to pa4965 ao P. aeruginosa of 50% (trembl|Q9HUK0) Pfam: Retroviral aspartyl protease no signal peptide 1 TMHs; Conserved hypothetical protein. (175 aa)    
Predicted Functional Partners:
prfC
Peptide chain release factor; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.714
yccA
Probable carrier/transport protein; Hypothetical protein PA2604. pir:D85624: 57% identity.73% similarity SIMILARITY:Belongs to the BI1 family. InterPro:Uncharacterized protein family UPF0005 IPR006213; Bax_inhbtr1. IPR006214; UPF0005. Pfam:ZIP: Zinc transporter Probable glutamatereceptor Signal peptide present (SignalP predicted) and transmembrane helices 7 (TMHMM predicted) Pfam:PF01027; UPF0005; InterPro: Uncharacterized protein family UPF0005 2_A_01_02: Multidrug resistance protein; Specificity unclear.
  
     0.449
azo0869
Conserved hypothetical secreted protein. Homology to rsc3264 of R. solanacearum (trembl|Q8XUC7). Smart: Bacterial OsmY and nodulation domain (BON) The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins; outside of this group the distribution is more disparate. signal [...]
  
     0.444
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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