Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo0108Conserved hypothetical secreted protein. Homology to XCC0740 of Xanthomonas campestris of 33% (trembl|Q8PCI6(SRS) Pfam: Glycosyl hydrolases family 2,TIM barrel domain This family contains beta-galactosidase,beta-mannosidase and beta-glucuronidase activities. No TMHs Signal peptide: present; Conserved hypothetical protein. (401 aa)    
Predicted Functional Partners:
gnl
Gluconolactonase precursor (D-glucono-delta-lactone lactonohydrolase).HYDROLYZES THE GLUCONOLACTONE FORMED BY GLUCOSE-FRUCTOSE OXIDOREDUCTASE AND THAT FORMED IN AEROBIC CONDITIONS BY THE GLUCOSE DEHYDROGENASE PRESENT. 30% SMP-30. Pfam:PF03758; SMP-30; 1. Signal peptide: present; High confidence in function and specificity.
    
  0.783
eglA
Putative endoglucanase precursor; 41% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1. Signal peptide: present; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
 
 0.776
spr1
Putative glucan 1,3-beta-glucosidase; Glucan 13-beta-glucosidase precursor (EC 3.2.1.58) (Exo-13-beta- glucanase).BETA-GLUCANASES PARTICIPATE IN THE METABOLISM OF BETA-GLUCAN THE MAIN STRUCTURAL COMPONENT OF THE CELL WALL. IT COULD ALSO FUNCTION BIOSYNTHETICALLY AS A TRANSGLYCOSYLASE. 33% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
 
 0.776
azo0750
Conserved hypothetical membrane protein. TREMBL:Q89QQ8: 34% identity This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permease proteins involved in the transport across the membrane of several compounds. This entry contains the inner components of this multicomponent transport system InterPro: IPR000522; FecD. Pfam: PF01032; FecCD ncs1: NCS1 nucleoside transporter fam Nonsecretory protein with signal peptide probability 0.203 (Signal P predicted). TMHMM predicted 9 transmembrane helices; Function unclear.
  
     0.707
barA
Putative sensor-regulator protein,; Specificity unclear.
    
 0.679
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
    
 0.679
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
    
 0.679
cyaY
Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
     
  0.679
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
    
 0.672
galE2
UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP- galactose 4-epimerase). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
 0.608
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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