STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuAPutative mannonate dehydratase; tremblnew|AAR36422:35% identity, 46% similarity EMBL:AE017218; AAR36422.1; TIGR:GSU3030; This Fe2+-requiring enzyme plays a role in D-glucuronate catabolism in Escherichia coli. Mannonate dehydratase converts D-mannonate to 2-dehydro-3-deoxy-D-gluconate. An apparent equivalog is found in a glucuronate utilization operon in Bacillus stearothermophilus T-6. Interpro:IPR004628;Man_dehyd SignalP predicted signal peptide present. No. of transmembrane helices: 1 (TMHMM predicted) pyrC_dimer: dihydroorotase homodimeric; Specificity unclear. (416 aa)    
Predicted Functional Partners:
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
 
   
 0.836
azo0148
Putative acyltransferase family protein; Similar to the Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-gpe acyltransferase); acyl-acyl carrier protein synthetase (acyl-acp synthetase)].Plays a role in lysophospholipid acylation. 25% Acyltransferase.IPR000873; AMP-bind. Pfam:PF01553; Acyltransferase; 1.PF00501; AMP-binding; 1. TMhelix:10; Function unclear.
       0.791
azo0147
Conserved hypothetical membrane protein. Homology to RS05051 of Ralstonia solanacearum of 45% (trembl|Q8Y1A4(SRS)). TMHMM2 reporting the presence of 26 TMH's. Signal P reporting Signal Peptide present. Coils2 program reporting presence of Coiled coil; Conserved hypothetical protein.
       0.732
nagAa
Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity.
    
  0.685
azo0152
Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein.
 
     0.665
xylE
Catechol 2,3-dioxygenase XylE catalyzes the ring cleavage of catechol and some substituted catechols. Similar to pir|JE0112 (52%), to trembl|Q45459 (48%)and to sprot|XYE2_PSEPU (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD000977): Extradiol ring-cleavage dioxygenase; Specificity unclear.
    
 0.638
smtB
Putative transcriptional repressor,; High confidence in function and specificity.
       0.620
azo3166
Hypothetical Protein,20% identity to TrEMBL;Q9HUK7. Very Bad homology with the hits in the DB over entire length of protein. No substantial good hits available. No signal peptide or TMH reported present.
  
     0.611
azo0166
Conserved hypothetical protein. Homology to ebA3023 of Azoarcus sp. EbN1 of 61% (trembl:Q5P4D4). No domains predicted. No TMHs. No signal peptide.
  
     0.596
azo3668
Conserved hypothetical membrane protein. Homology to rs05101 R. solanacearum of 36% (trembl|Q8Y1D8(SRS)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein.
  
     0.583
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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