Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ubiE1Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (245 aa)    
Predicted Functional Partners:
ubiH
Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein; ubiH; aromatic-ring hydroxylase (flavoprotein monooxygenase) Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone. Ubiquinone biosynthesis pathway, by similarity; High confidence in function and specificity.
  
  
 0.951
azo0161
Conserved hypothetical protein. Homology to rsc0460 of R. solanacearum of 39% (trembl|Q8Y276(SRS) Pfam: DUF1243 This family consists of a number of hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown. no signal peptide no TMHs.
  
 
 0.890
azo0372
Conserved hypothetical protein; Entry name SWISSPROT:YHBT_ECOLI Prim. accession # P45474 InterPro IPR003033; SCP2. Pfam PF02036; SCP2; 1. Prediction: Non-secretory protein Signal peptide probability: 0.001 Number of predicted TMHs: 0 Identities = 46/107 (42%).
     
  0.881
azo0373
Conserved hypothetical peptidase. Homology to Rsp0969 of R. solanacearum of 51% (trembl|Q8XR90). Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
     
  0.881
azo0374
Conserved hypothetical peptidase. Homology to cv4084 of C. violaceum of 64% (trembl|Q7NQQ39. Pfam: Peptidas family U32 no signal peptide no TMHs; Family membership.
     
  0.881
azo0163
Conserved hypothetical protein. Homology to rs04443 of R. solanacearum of 69% (trembl|Q8Y279). Pfam: PF06155,Protein of unknown function (DUF971) Interpro: IPR010376; This family consists of several short bacterial proteins and one sequence (Q8RZ62) from Oryza sativa. The function of this family is unknown. No Signal Peptide. No TMH present.
       0.806
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.758
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
     
 0.749
ispB
Octaprenyl-diphosphate synthase; Polyprenyl synthetase,82% identity to TrEMBL;Q5P1Y1. Has Pfam;PF00348, Polyprenyl synthetase.(IPR000092,Polyprenyl_synt)A variety of isoprenoid compounds are synthesized by various organisms. For example in eukaryotes the isoprenoid biosynthetic pathway is responsible for the synthesis of a variety of end products including cholesterol, dolichol, ubiquinone or coenzyme Q. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Among the enzymes that participate in that pathway, are a number of [...]
 
 
 0.693
azo2022
Conserved hypotheticalsecreted protein. Homology to bll4707 of B.japonicum of 40% (tremble:Q89L41). No domains predicted. Signal P reporting signal peptide present. No TMH reported to be present; Conserved hypothetical protein.
     
 0.624
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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