STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreDRod shape-determining protein mreD. Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins; High confidence in function and specificity. (173 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
 
 
 0.990
rodA
Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
  
 0.916
pbpA
Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
  
 0.895
minC
Putative cell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.884
mreB
Rod shape-determining protein mreB. INVOLVED IN FORMATION OF THE ROD SHAPE OF THE CELL. MAY ACT AS A NEGATIVE REGULATOR OF FTSI. InterPro: Cell shape determining protein MreB/Mrl mreB: cell shape determining protein; High confidence in function and specificity.
  
  
 0.852
rlpA
Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
     
 0.836
minD
Septum site-determining protein minD (Cell division inhibitor minD); High confidence in function and specificity.
  
  
 0.801
FtsQ
Putative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
  
 0.733
holA
DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; High confidence in function and specificity.
  
     0.715
azo3984
Conserved hypothetical secreted protein. Homology to RS02253 of R.solanacearum of 32% (trembl|Q8Y3A4(SRS)). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein.
  
     0.685
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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