Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hvrA1Putative trans-acting regulatory protein. Homology to hvrA of R. capsulatus of 27% (sprot|HVRA_RHOCA). The histone-like nucleoid-structuring (H-NS) protein belongs to a family of bacterial proteins that play a role in the formation of nucleoid structure and affect gene expression under certain conditions (e.g. light). Interpro: Histone -like nucleotide-structuring protein H-Ns (IPR001801) Pfam: H-NS histone family no signal peptide no TMHs; Family membership. (132 aa)    
Predicted Functional Partners:
azo0195
Conserved hypothetical secreted protein. Homology to CV3728 of Chromobacterium violaceum of 57% (tremble:Q7NRQ2) No domains predicted. No TMHs signal peptide present; Conserved hypothetical protein.
       0.628
ihfA
Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
 0.619
ihfB
Probable integration host factor, beta-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
 0.528
trxC1
Probable protein-disulfide reductase. Homology with trxC of E. coli of 45% (AAB88587). Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. InterPro: Thioredoxin Tigrfam: redox_disulf_1: redox-active disulfide Pfam: Thioredoxin no TMHs no signal peptide; Family membership.
       0.521
hupB
DNA-binding protein HU (DNA-binding protein II); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
   
 0.520
azo1525
Conserved hypothetical protein. Homology to PA3209 of Pseudomonas aeruginosa of 43% (trembl:Q9HZ31). Has PF03692, Uncharacterised protein family (UPF0153); IPR005358;This family of proteins contain 8 conserved cysteines that may form a metal binding site. The function of these proteins is unknown but might be an Fe-S cluster as part of an oxidoreductase complex. No signal peptide. No TMHs.
  
     0.422
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (12%) [HD]