| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | azo3364 | azo1036 | azo3364 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | 0.673 |
| aroC | pabB | azo1036 | azo0198 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.969 |
| aroC | pheA | azo1036 | azo1068 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.987 |
| aroC | trpA | azo1036 | azo1048 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.890 |
| aroC | trpB | azo1036 | azo1047 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.698 |
| aroC | trpC | azo1036 | azo3322 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase (IGPS). catalytic activity:1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + co(2) + h(2)o. pathway: tryptophan biosynthesis; fourth step. InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. | 0.766 |
| aroC | trpD | azo1036 | azo3323 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.815 |
| aroC | trpF | azo1036 | azo1046 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity. | 0.670 |
| aroC | trpG | azo1036 | azo3324 | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component II (Glutamine amido-transferase). catalytic activity: chorismate + l-glutamine = anthranilate + pyruvate + l-glutamate. pathway: tryptophan biosynthesis; first step. TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | 0.953 |
| azo3364 | aroC | azo3364 | azo1036 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | AroC protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.673 |
| azo3364 | pabB | azo3364 | azo0198 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.988 |
| azo3364 | pheA | azo3364 | azo1068 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity. | 0.894 |
| azo3364 | trpA | azo3364 | azo1048 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.869 |
| azo3364 | trpB | azo3364 | azo1047 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.933 |
| azo3364 | trpC | azo3364 | azo3322 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Indole-3-glycerol phosphate synthase (IGPS). catalytic activity:1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + co(2) + h(2)o. pathway: tryptophan biosynthesis; fourth step. InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family. | 0.934 |
| azo3364 | trpD | azo3364 | azo3323 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | 1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.585 |
| azo3364 | trpF | azo3364 | azo1046 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | N-(5-phosphoribosyl)anthranilate isomerase (PRAI) catalyzes the third step of tryptophan biosynthesis. Similar to sprot|TRPF_RALSO (56%) and to sprot|TRPF_PSEAE (58%). Pfam (PF00697): N-(5'phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity. | 0.938 |
| azo3364 | trpG | azo3364 | azo3324 | The glycosyl transferase family includes anthranilate phosphoribosyltransferase (TrpD, EC: 2.4.2.18) and thymidine phosphorylase (EC: 2.4.2.2). All these proteins can transfer a phosphorylated ribose substrate. Similar to sprot|YBIB_ECOLI (40%) and to sprot|TRPD_SULSO (25%). Pfam (PF02885): Glycosyl transferase, family 3; Family membership. | Anthranilate synthase component II (Glutamine amido-transferase). catalytic activity: chorismate + l-glutamine = anthranilate + pyruvate + l-glutamate. pathway: tryptophan biosynthesis; first step. TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | 0.939 |
| folP | pabB | azo1388 | azo0198 | Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase). DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide (By similarity); High confidence in function and specificity. | Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear. | 0.964 |
| folP | trpG | azo1388 | azo3324 | Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase). DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide (By similarity); High confidence in function and specificity. | Anthranilate synthase component II (Glutamine amido-transferase). catalytic activity: chorismate + l-glutamine = anthranilate + pyruvate + l-glutamate. pathway: tryptophan biosynthesis; first step. TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | 0.707 |
