STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aldHPutative aldehyde dehydrogenase (NAD+) (EC 1.2.1.3). Homology to adlH of E. coli of 35% (sprot|DHAL_ECOLI). Aldehyde dehydrogenases (EC: 1.2.1.3 and EC: 1.2.1.5) are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. (494 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
  
 
 0.837
yhdH
TREMBL:Q881C6:69% identity; 83% similarity. Alcohol dehydrogenase (EC: 1.1.1.1) (ADH) catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD: Ethanol + NAD = Acetaldehyde + NADH Protein yhdH. InterPro:IPR002085; Adh_zn_family. Pfam:PF00107; ADH_zinc_N; FAD binding domain InterPro: Zinc-containing alcohol dehydrogenase superfamily TIGRFAM:tdh: L-threonine 3-dehydrogenase; High confidence in function and specificity.
    
 0.784
ordL
This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase, D-aspartate oxidase. Similar to trembl|Q88AY5 (61%) and to sprot|ORDL_ECOLI (32%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site; Family membership.
 
 
 0.734
hadL
Probable 2-haloalkanoic acid dehalogenase (EC 3.8.1.2) (L-2-haloacid dehalogenase) (Halocarboxylic acid halidohydrolase). TREMBL:Q92Y68: 68% identity, 82% similarity These proteins catalyze the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids [1]. They belong to the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases InterPro:IPR006328; HAD_II. IPR006388; HAD_SF_IA_v2. IPR005834; Hydrolase. Pfam PF00702; Hydrolase rpiB_lacA_lacB: sugar-phosphate isomer No signal peptide No transmembrane helices; High [...]
  
  0.701
putA
Probable bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 0.683
azo0214
Conserved hypothetical acetyltransferase. Homology to putative acetaltransferase (GNAT family) of P. syringae of 42% (trembl|Q88AY8). Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHs; Family membership.
 
     0.658
nagAa
Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity.
    
 0.637
adhA
Putative Alcohol dehydrogenase. Homology to adh-HT of B. stearothermophilus (sprot|ADH3_BACST) THERMOSTABLE AND THERMOPHILIC NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. BEARS MAINLY AN ETHANOL-DEHYDROGENASE ACTIVITY. CATALYTIC ACTIVITY:An alcohol + NAD(+) = an aldehyde or ketone + NADH. COFACTOR: Binds 2 zinc ions per subunit (By similarity). Pfam: Zinc-binding dehydrogenase Tirgfam: tdh: L-threonine 3-dehydrogenase no signal peptide no TMHs; Family membership.
  
 0.636
azo1971
Putative alcohol dehydrogenase; SPROT:ADH1_BACST:31% identity; 45% similarity Alcohol dehydrogenase (EC 1.1.1.1) (ADH-T). THERMOSTABLE NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. an alcohol + nad(+) = an aldehyde or ketone + nadh. cofactor:binds 2 zinc ions per subunit (by similarity). InterPro: IPR002328; ADH_zinc. IPR002085:Adh_zn_family. Pfam:PF00107; ADH_zinc_N tdh: L-threonine 3-dehydrogenase; Specificity unclear.
  
 0.632
fumB
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
 0.618
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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