STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hadLProbable 2-haloalkanoic acid dehalogenase (EC 3.8.1.2) (L-2-haloacid dehalogenase) (Halocarboxylic acid halidohydrolase). TREMBL:Q92Y68: 68% identity, 82% similarity These proteins catalyze the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids [1]. They belong to the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases InterPro:IPR006328; HAD_II. IPR006388; HAD_SF_IA_v2. IPR005834; Hydrolase. Pfam PF00702; Hydrolase rpiB_lacA_lacB: sugar-phosphate isomer No signal peptide No transmembrane helices; High [...] (221 aa)    
Predicted Functional Partners:
ordL
This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase, D-aspartate oxidase. Similar to trembl|Q88AY5 (61%) and to sprot|ORDL_ECOLI (32%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site; Family membership.
 
   
 0.924
dppA
Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide periplasmic-binding protein dppA in E.coli. DIPEPTIDE-BINDING PROTEIN OF AN OSMOTIC-SHOCKABLE TRANSPORT SYSTEM. DPPA IS ALSO REQUIRED FOR PEPTIDE CHEMOTAXIS. InterPro: Bacterial extracellular solute-binding protein family 5 Signal peptide; Specificity unclear.
 
   
 0.909
dppD
Putative dipeptide transport system, ATP-binding protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide transport membrane protein, DppD in E.coli Probably responsible for energy coupling to the transport system; Specificity unclear.
 
     0.882
dppC
ABC transporter, permease protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease protein, DppC in E.coli; Specificity unclear.
 
     0.880
dppB
Putative dipeptide transport system, permease protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease protein, DppB in E.coli; Specificity unclear.
 
     0.878
azo0214
Conserved hypothetical acetyltransferase. Homology to putative acetaltransferase (GNAT family) of P. syringae of 42% (trembl|Q88AY8). Pfam: Acetyltransferase (GNAT) family no signal peptide no TMHs; Family membership.
 
     0.837
ribD
AMP deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.814
ooxA
Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
 
 
   0.773
azo0211
Conserved hypothetical protein.
 
     0.768
agaE
Sarcosine oxidase,subunit beta counts to the FAD dependent oxidoreductases. Similar to trembl|Q88AX8 (49%) and to trembl|Q987J9 (43%). Pfam (PF01266): FAD dependent oxidoreductase Pfam (PF01494): FAD binding domain Pfam (PF00070): Pyridine nucleotide-disulphide oxidoreductase; Function unclear.
  
   
 0.734
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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