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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
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azo0289ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8R788 (35% identity); TREMBL:Q81S77 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transpor [...] (307 aa)    
Predicted Functional Partners:
azo0286
Putative ABC transporter permease; Similar to TREMBL:Q7NFQ1 (27% identity); TREMBL:Q97E48 (20% identity); TREMBL:Q8FWI9 (21% identity). TMHMM predicting six transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Specificity unclear.
 
 
 0.930
azo0290
Conserved hypothetical protein. Homology to Daro03001929 of Dechloromonas aromatica of 68% (gi|53730629|ref|ZP_00348881.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.900
azo0291
Conserved hypothetical protein. Homology to Daro03001928 of Dechloromonas aromatica of 59% (gi|41724574|ref|ZP_00151411.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.897
darA
Probable dialkylrecorsinol condensing enzyme. Homology to darA of P. aurantiaca of 56% (trembl|Q84H30(SRS)) no domains predicted no signal peptide 1 TMHs; Family membership.
 
     0.881
darB
3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta- ketoacyl-ACP synthase III) (KAS III). Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids (By similarit [...]
 
     0.854
cbiO
Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity.
 
  
 
0.783
azo0294
Putative penicillin-binding protein; INVOLVED IN CELL WALL BIOSYNTHESIS AND MAY ALSO ACT AS A SENSOR OF EXTERNAL PENICILLINS, TREMBL:Q7UMP8 (30% identity); TREMBL:Q988N4 (27% identity); Family membership.
 
   
 0.770
nodJ
ABC transporter permease NodJ; Forms with NodI a membrane transport complex involved in the nodulation process. it probably exports a modified beta-1,4-linked n-acetylglucosamine oligosaccharide. Belongs to the ABC-2 integral membrane protein family, TREMBL:Q7WHD1 (49% identity); SWISSPROT:O52619 (49% identity). InterPro (IPR000412): ABC transporter, family 2. Pfam (PF01061): ABC-2 type transporter. TMHMM reporting six transmembrane helices. TC (3.A.1.102): The Lipooligosaccharide Exporter (LOSE) Family; High confidence in function and specificity.
 
 
 0.768
nosY
Membrane protein nosY precursor.INVOLVED IN COPPER PROCESSING. Part of the ABC transporter complex nosDFY involved in copper import. Probably responsible for the translocation of the substrate across the membrane. 43% Similar to the copper permease protein, nosY in P.stutzeri. TREMBL:Q9F0W1 InterPro:IPR001117; Cu-oxidase. SignalP: present. Number of predicted TMHs:6; High confidence in function and specificity.
  
 0.757
azo3353
Conserved hypothetical membrane protein; In Myxococcus xanthus pilI are co-transcribed with pilH an ABC transporter homologue required for type IV pilus biogenesis and social gliding. pilI appear to be functionally related to pilH. Similar to membrane protein of Geobacter sulfurreducens PCA (14%) and weak; Conserved hypothetical protein.
  
 0.722
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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