STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
azo0294Putative penicillin-binding protein; INVOLVED IN CELL WALL BIOSYNTHESIS AND MAY ALSO ACT AS A SENSOR OF EXTERNAL PENICILLINS, TREMBL:Q7UMP8 (30% identity); TREMBL:Q988N4 (27% identity); Family membership. (604 aa)    
Predicted Functional Partners:
darA
Probable dialkylrecorsinol condensing enzyme. Homology to darA of P. aurantiaca of 56% (trembl|Q84H30(SRS)) no domains predicted no signal peptide 1 TMHs; Family membership.
 
     0.793
darB
3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta- ketoacyl-ACP synthase III) (KAS III). Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids (By similarit [...]
 
     0.787
azo0290
Conserved hypothetical protein. Homology to Daro03001929 of Dechloromonas aromatica of 68% (gi|53730629|ref|ZP_00348881.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.778
azo0291
Conserved hypothetical protein. Homology to Daro03001928 of Dechloromonas aromatica of 59% (gi|41724574|ref|ZP_00151411.1|(NBCI ENTREZ)). No domains predicted. No TMHs. No signal peptide.
 
     0.778
azo0289
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8R788 (35% identity); TREMBL:Q81S77 (37% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transpor [...]
 
     0.769
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.768
azo3973
Hypothetical protein. no homology of the entire protein to the data bank. Pfam: putative peptidoglycan binding domain. This domain, peptidoglycan binding domain 1, may have a general peptidoglycan binding function. It is composed of three alpha helices and is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. no signal peptide. no TMHs.
     
 0.643
nagZ1
Putative beta-hexosaminidase; (N-acetyl-beta-glucosaminidase)(Beta-N- acetylhexosaminidase). Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity). Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D-glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta-GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. May play a role in signal transduction between host and organism. 34% Glyco_hydro_3N. Pfam:PF00933; Glyco_hydro_3; 1. TMhelix:2; High confidence in function and specificity.
  
 
 0.599
nagZ2
Putative beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
 
 0.599
azo0286
Putative ABC transporter permease; Similar to TREMBL:Q7NFQ1 (27% identity); TREMBL:Q97E48 (20% identity); TREMBL:Q8FWI9 (21% identity). TMHMM predicting six transmembrane helices. TC (2.A.6.2): The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Specificity unclear.
 
   
 0.560
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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