STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaYProbable phenyl acetic acid degradation protein; Pathway:carnitine metabolism (conversion of carnitine to gamma-butyrobetaine). TREMBL:Q9F9V3: 71% identity, 83% similarity similarity:belongs to the transferase hexapeptide repeat family Carnitine operon protein caiE. InterPro:IPR001451; Hexapep_transf. Pfam:PF00132; Hexapep InterPro: Bacterial transferase hexapeptide repeat TIGR00094: conserved hypothetical protein; High confidence in function and specificity. (202 aa)    
Predicted Functional Partners:
azo3977
Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
    
 0.914
azo0297
Conserved hypothetical protein, 66% similarity to TrEMBL; Q6NA86. Signal peptide present. No TMH reported present.
       0.785
paaZ
Conserved hypothetical dehydrogenase. Homology to paaZ of A. evansii of 83% (trembl|Q9F9V2). Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership.
     
 0.648
paaI
Phenylacetic acid degradation protein PaaI; Phenylacetic acid aerobic catabolism. Similar to TREMBL:Q9F9V0 (74% identity); SWISSPROT:P76084 (48% identity). InterPro (IPR003736): Phenylacetic acid degradation-related protein. Pfam (DUF157): Uncharacterized protein PaaI, COG2050; High confidence in function and specificity.
 
   
 0.506
azo0296
InterPro:IPR001279- Metallo-beta-lactamase superfamily,glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. TREMBL:Q7WEK1-55% Identity. Pfam-Presence of phosphoribosyltransferase, tissue factor, and GMP reductaseC like domains Signal P predicting signal peptide and TMHMM predicting transmembrane helices. ccoP: cytochrome c oxidase cbb3-type s; High confidence in function and specificity.
       0.503
mnaA
UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity.
    
  0.456
paaA
Phenylacetic acid degradation protein [paaA],86% identity(91% similarity) to TrEMBL;Q9F9U9. 72% identity to TrEMBL;Q7WGX6, Q8XS77 Has PF05138, Phenylacetic acid catabolic protein;IPR007814, PaaA_PaaC; This family includes proteins such as PaaA and PaaC that are part of a catabolic pathway of phenylacetic acid. These proteins may form part of a dioxygenase complex. No Signal Peptide or TMH present; High confidence in function and specificity.
 
   
 0.428
paaH1
Probable 3-hydroxybutyryl-CoA dehydrogenase; Activity:-3-acetoacetyl-CoA + NADPH = (S)-3-hydroxybutanoyl-CoA + NADP+ Entry name TREMBL:Q9F9V1 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR002110; ANK. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 2. PF02737; 3HCDH_N; 1. Identities = 344/510 (67%) Prediction: Signal peptide Signal peptide probability: 0.660 Number of predicted TMHs: 1; High confidence in function and specificity.
 
   
 0.424
paaB
Phenylacetic acid degradation protein PaaB; May be part of a multicomponent oxygenase involved in phenylacetyl-coa hydroxylation. Phenylacetic acid aerobic catabolism pathway, TREMBL:Q8XS76 (75% identity); SWISSPROT:P76078 (61% identity); High confidence in function and specificity.
 
   
 0.422
paaG1
Probable enoyl-CoA hydratase. Homology to paaG of E. coli of 60% (sprot|PAAG_ECOLI(SRS) COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). Activity:- (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Interpro: Enoyl-CoA hydratase/isomerase (IPR001753) Pfam: Enoyl-CoA hydratase/isomerase no signal peptide no TMHs; High confidence in function and specificity.
 
   
 0.409
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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